Assay Detail
Binding
CHEMBL672794
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]raclopride binding to Dopamine receptor D2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Novel (R)-2-amino-5-fluorotetralins: dopaminergic antagonists and inverse agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.47 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL138998 | — | — | 1 | 7.77 |
| CHEMBL139089 | — | — | 1 | 7.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL138998 | — | Ki | = | 16.9 | nM | 7.77 |
| CHEMBL139089 | — | Ki | = | 68.2 | nM | 7.17 |