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Assay Detail

CHEMBL672886

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Binding
Inhibitory activity against pig kidney L-aromatic amino acid decarboxylase (Dopa decarboxylase)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Aromatic-L-amino-acid decarboxylase (CHEMBL2841)
Type SINGLE PROTEIN
Organism Sus scrofa

Publication

Inhibition of pig kidney L-aromatic amino acid decarboxylase by 2,3-methano-m-tyrosines.
Ahmad S, Phillips RS, Stammer CH.
J Med Chem (1992) 35 : 1410 -1417
PubMed 1573634 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 4.31 4.31

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2368541 1 4.31
CHEMBL30857 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2368541 Ki = 49000.0 nM 4.31
CHEMBL30857 Ki = 630000.0 nM -