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Assay Detail

CHEMBL672954

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding Affinity was tested on High Affinity Site of Dopamine receptor D2S
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL217)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Conjugated enynes as nonaromatic catechol bioisosteres: synthesis, binding experiments, and computational studies of novel dopamine receptor agonists recognizing preferentially the D(3) subtype.
Hübner H, Haubmann C, Utz W, Gmeiner P.
J Med Chem (2000) 43 : 756 -762
PubMed 10691700 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.82 4.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL166325 1 4.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL166325 Ki = 15000.0 nM 4.82