Assay Detail
Binding
CHEMBL673119
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Compound was evaluated for binding affinity against Dopamine receptor D3 in CHO cells using [125I]iodosulpiride as the radioligand
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL414628 | — | — | 1 | 6.00 |
| CHEMBL157910 | — | — | 1 | - |
| CHEMBL154274 | — | — | 1 | - |
| CHEMBL329383 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL414628 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL157910 | — | Ki | > | 3981.07 | nM | - |
| CHEMBL154274 | — | Ki | > | 5011.87 | nM | - |
| CHEMBL329383 | — | Ki | > | 5011.87 | nM | - |