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Assay Detail

CHEMBL674048

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Binding
Binding affinity towards cloned human Dopamine receptor D4
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(4) dopamine receptor (CHEMBL219)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine D4 receptor ligand.
Macchia B, Cervetto L, Demontis GC, Domiano P, Longoni B, Macchia M, Minutolo F, Orlandini E, Ortore G, Papi C.
Bioorg Med Chem Lett (2001) 11 : 223 -226
PubMed 11206464 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.05 8.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL45244 PD-168,077 1 8.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL45244 PD-168,077 Ki = 9.0 nM 8.05