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Assay Detail

CHEMBL674131

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity of compound towards human Dopamine receptor D4 by displacing [125I]-iodosulpiride expressed in CHO cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type CHO
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(4) dopamine receptor (CHEMBL219)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

N-(omega-(4-(2-methoxyphenyl)piperazin-1-yl)alkyl)carboxamides as dopamine D2 and D3 receptor ligands.
Hackling A, Ghosh R, Perachon S, Mann A, Höltje HD, Wermuth CG, Schwartz JC, Sippl W, Sokoloff P, Stark H.
J Med Chem (2003) 46 : 3883 -3899
PubMed 12930150 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.41 9.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL279247 1 9.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL279247 Ki = 0.39 nM 9.41