Assay Detail
Binding
CHEMBL674888
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Binding affinity against Elastase.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Protease inhibitors: current status and future prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.92 | 10.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL114992 | — | — | 1 | 10.89 |
| CHEMBL276307 | — | — | 1 | 9.02 |
| CHEMBL303493 | — | — | 1 | 8.03 |
| CHEMBL428848 | — | — | 1 | 7.00 |
| CHEMBL76688 | SIVELESTAT | 3.0 | 1 | 6.70 |
| CHEMBL326073 | — | — | 1 | 5.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL114992 | — | Ki | = | 0.013 | nM | 10.89 |
| CHEMBL276307 | — | Ki | = | 0.95 | nM | 9.02 |
| CHEMBL303493 | — | Ki | = | 9.4 | nM | 8.03 |
| CHEMBL428848 | — | Ki | = | 101.0 | nM | 7.00 |
| CHEMBL76688 | SIVELESTAT | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL326073 | — | Ki | = | 1380.0 | nM | 5.86 |