Assay Detail
Functional
CHEMBL675106
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Tested for 50% inhibition against EMT-6 murine mammary carcinoma cell under normal oxygenated condition
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | EMT6 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of the antitumor activity of 4,5-diamino-substituted 1,2-benzoquinones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.85 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51276 | — | — | 1 | 6.40 |
| CHEMBL36016 | DIAZIQUONE | 2.0 | 1 | 5.30 |
| CHEMBL51774 | — | — | 1 | - |
| CHEMBL298111 | — | — | 1 | - |
| CHEMBL301345 | — | — | 1 | - |
| CHEMBL299085 | — | — | 1 | - |
| CHEMBL50792 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51276 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL36016 | DIAZIQUONE | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL51774 | — | IC50 | = | 125000.0 | nM | - |
| CHEMBL298111 | — | IC50 | = | 500000.0 | nM | - |
| CHEMBL301345 | — | IC50 | > | 500000.0 | nM | - |
| CHEMBL299085 | — | IC50 | = | 500000.0 | nM | - |
| CHEMBL50792 | — | IC50 | = | 500000.0 | nM | - |