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Assay Detail

CHEMBL675130

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Functional
Effective concentration for Dopamine receptor D3 was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cercopithecidae
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL217)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

N-(omega-(4-(2-methoxyphenyl)piperazin-1-yl)alkyl)carboxamides as dopamine D2 and D3 receptor ligands.
Hackling A, Ghosh R, Perachon S, Mann A, Höltje HD, Wermuth CG, Schwartz JC, Sippl W, Sokoloff P, Stark H.
J Med Chem (2003) 46 : 3883 -3899
PubMed 12930150 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 8.30 8.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL129022 1 8.60
CHEMBL126725 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL129022 EC50 = 2.5 nM 8.60
CHEMBL126725 EC50 = 10.0 nM 8.00