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Assay Detail

CHEMBL675133

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Effective concentration for Dopamine receptor D3 was determined in monkeys
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cercopithecidae
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

D(3) dopamine receptor (CHEMBL2304406)
Type SINGLE PROTEIN
Organism Chlorocebus aethiops

Publication

N-(omega-(4-(2-methoxyphenyl)piperazin-1-yl)alkyl)carboxamides as dopamine D2 and D3 receptor ligands.
Hackling A, Ghosh R, Perachon S, Mann A, Höltje HD, Wermuth CG, Schwartz JC, Sippl W, Sokoloff P, Stark H.
J Med Chem (2003) 46 : 3883 -3899
PubMed 12930150 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL25236 BP-897 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL25236 BP-897 EC50 = 3.0 nM 8.52