Assay Detail
Functional
CHEMBL675199
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for the effective concentration against human D4.2 receptor in CHO 10001 cells established in mitogenesis assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.37 | 8.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL160626 | — | — | 1 | 8.82 |
| CHEMBL160932 | — | — | 1 | 7.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL160626 | — | EC50 | = | 1.5 | nM | 8.82 |
| CHEMBL160932 | — | EC50 | = | 12.0 | nM | 7.92 |