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Assay Detail

CHEMBL675324

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Functional
Cytotoxicity on EMT6 cells growth (reduce cell number by 50%).
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type EMT6
Confidence 1 — Organism
Curated By Intermediate

Target

EMT6 (CHEMBL614294)
Type CELL-LINE
Organism Mus musculus

Publication

N-Substituted 2-(2,6-dinitrophenylamino)propanamides: novel prodrugs that release a primary amine via nitroreduction and intramolecular cyclization.
Sykes BM, Atwell GJ, Hogg A, Wilson WR, O'Connor CJ, Denny WA.
J Med Chem (1999) 42 : 346 -355
PubMed 9986704 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.92 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL275497 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL275497 IC50 = 1200.0 nM 5.92