Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL675353

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for the enzyme inhibitory activity against Human Leukocyte Elastase (HLE) at 28 uM concentration
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Neutrophil elastase (CHEMBL248)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G.
Zembower DE, Kam CM, Powers JC, Zalkow LH.
J Med Chem (1992) 35 : 1597 -1605
PubMed 1578486 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.75 4.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL41092 CHRYSOPHANOL 1 4.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL41092 CHRYSOPHANOL IC50 = 18000.0 nM 4.75