Assay Detail
Functional
CHEMBL675469
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In vitro growth inhibitory activity against Encephalitozoon cuniculi grown on RK-13 cells infected as a monolayer
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Encephalitozoon cuniculi |
| Cell Type | RK-13 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel alkylpolyamine analogues that possess both antitrypanosomal and antimicrosporidial activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.39 | 6.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL289450 | — | — | 1 | 6.33 |
| CHEMBL40414 | — | — | 1 | 4.44 |
| CHEMBL43494 | — | — | 1 | - |
| CHEMBL44040 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL289450 | — | IC50 | = | 470.0 | nM | 6.33 |
| CHEMBL40414 | — | IC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL43494 | — | IC50 | = | 204000.0 | nM | - |
| CHEMBL44040 | — | IC50 | = | 232000.0 | nM | - |