Assay Detail
Functional
CHEMBL675689
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for its inhibitory activity against P-glycoprotein (Pgp) using potentiation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | EMT6 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Studies on quinazolinones as dual inhibitors of Pgp and MRP1 in multidrug resistance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.48 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL421980 | — | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL421980 | — | EC50 | = | 3300.0 | nM | 5.48 |