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Assay Detail

CHEMBL676200

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against human Elastase at 100 uM concentration
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Neutrophil elastase (CHEMBL248)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

2-chloro-3-substituted-1,4-naphthoquinone inactivators of human cytomegalovirus protease.
Ertl P, Cooper D, Allen G, Slater MJ.
Bioorg Med Chem Lett (1999) 9 : 2863 -2866
PubMed 10522707 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.52 4.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL318067 1 4.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL318067 IC50 = 30000.0 nM 4.52