Assay Detail
Binding
CHEMBL676298
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Inhibitory activity against [125I]- NCQ298 binding to dopamine receptor D3 in Sf 9 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | Sf 9 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of (R,S)-trans-8-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetral in (trans-8-OH-PIPAT): a new 5-HT1A receptor ligand.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.35 | 8.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285755 | — | — | 1 | 8.54 |
| CHEMBL284716 | — | — | 1 | 6.90 |
| CHEMBL56 | 8-OH-DPAT | — | 1 | 6.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285755 | — | Ki | = | 2.9 | nM | 8.54 |
| CHEMBL284716 | — | Ki | = | 125.0 | nM | 6.90 |
| CHEMBL56 | 8-OH-DPAT | Ki | = | 251.0 | nM | 6.60 |