Assay Detail
Functional
CHEMBL676539
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration of compound against formation of Enterovirus 71 (2231) genotype C plaque in plaque reduction assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterovirus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and structure-activity relationships of pyrazolo[3,4-d]pyrimidines: a novel class of potent enterovirus inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.11 | 6.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL84696 | — | — | 1 | 6.28 |
| CHEMBL291183 | — | — | 1 | 5.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL84696 | — | IC50 | = | 520.0 | nM | 6.28 |
| CHEMBL291183 | — | IC50 | = | 1150.0 | nM | 5.94 |