Assay Detail
Functional
CHEMBL676543
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Inhibition concentration against EV-71 (2231) genotype C
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterovirus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and structure-activity relationship of pyridyl imidazolidinones: a novel class of potent and selective human enterovirus 71 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.91 | 5.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL291183 | — | — | 1 | 5.94 |
| CHEMBL296696 | — | — | 1 | 5.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL291183 | — | IC50 | = | 1150.0 | nM | 5.94 |
| CHEMBL296696 | — | IC50 | = | 1350.0 | nM | 5.87 |