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Assay Detail

CHEMBL676646

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration against endotheline ETB receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Endothelin receptor type B (CHEMBL1785)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Selective optimization of side activities: another way for drug discovery.
Wermuth CG.
J Med Chem (2004) 47 : 1303 -1314
PubMed 14998318 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.73 4.73

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL24461 1 4.73

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL24461 Ki = 18700.0 nM 4.73