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Assay Detail

CHEMBL676744

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested for the binding affinity against human leukocyte elastase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Neutrophil elastase (CHEMBL248)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A general synthesis of 4-alkyl/aryl substituted saccharins
Subramanyam C, Bell MR
Bioorg Med Chem Lett (1991) 1 : 733 -736
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.82 7.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL50803 1 7.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL50803 Ki = 15.0 nM 7.82