Assay Detail
Binding
CHEMBL677065
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for inhibition of the Folate hydrolase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated alpha-linked acidic dipeptidase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.15 | 9.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL47009 | — | — | 1 | 9.56 |
| CHEMBL156643 | — | — | 1 | 8.72 |
| CHEMBL132183 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL47009 | — | Ki | = | 0.275 | nM | 9.56 |
| CHEMBL156643 | — | Ki | = | 1.89 | nM | 8.72 |
| CHEMBL132183 | — | Ki | = | 700.0 | nM | 6.16 |