Assay Detail
Binding
CHEMBL677079
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Inhibitory concentration required against Fucosyltransferase 6
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 (CHEMBL4443) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.65 | 5.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL610389 | — | — | 1 | 5.86 |
| CHEMBL610391 | — | — | 1 | 5.79 |
| CHEMBL610390 | — | — | 1 | 5.72 |
| CHEMBL611881 | — | — | 1 | 5.48 |
| CHEMBL608046 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL610389 | — | IC50 | = | 1394.0 | nM | 5.86 |
| CHEMBL610391 | — | IC50 | = | 1618.0 | nM | 5.79 |
| CHEMBL610390 | — | IC50 | = | 1893.0 | nM | 5.72 |
| CHEMBL611881 | — | IC50 | = | 3338.0 | nM | 5.48 |
| CHEMBL608046 | — | IC50 | = | 3957.0 | nM | 5.40 |