Assay Detail
Binding
CHEMBL677158
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Tested for 50% inhibition of generation of Human estrogen receptor polymerase chain reaction(PCR) products
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis and antitumor activity of new benzoheterocyclic derivatives of distamycin A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 8.41 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL552863 | — | — | 1 | 9.00 |
| CHEMBL536328 | — | — | 1 | 9.00 |
| CHEMBL540313 | — | — | 1 | 8.52 |
| CHEMBL554247 | — | — | 1 | 8.30 |
| CHEMBL552690 | — | — | 1 | 8.30 |
| CHEMBL554189 | — | — | 1 | 8.30 |
| CHEMBL554353 | — | — | 1 | 8.12 |
| CHEMBL11252 | STALLIMYCIN | 2.0 | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL552863 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL536328 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL540313 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL554247 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL552690 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL554189 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL554353 | — | IC50 | = | 7.5 | nM | 8.12 |
| CHEMBL11252 | STALLIMYCIN | IC50 | = | 20.0 | nM | 7.70 |