Assay Detail
Functional
CHEMBL677159
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human estrogen receptor(ER) polymerase-chain reaction product
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Expert |
Publication
Design, synthesis and biological activity of a pyrrolo [2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.57 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL102341 | — | — | 1 | 5.10 |
| CHEMBL11252 | STALLIMYCIN | 2.0 | 1 | 4.30 |
| CHEMBL101290 | — | — | 1 | 4.30 |
| CHEMBL300580 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL102341 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL11252 | STALLIMYCIN | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL101290 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL300580 | — | IC50 | > | 300000.0 | nM | - |