Assay Detail
Functional
CHEMBL677167
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Src-transformed fibroblast cell proliferation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | Fibroblast |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Proto-oncogene tyrosine-protein kinase Src (CHEMBL267) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
4-Anilino-3-cyanobenzo[g]quinolines as kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.15 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL335025 | — | — | 1 | 6.68 |
| CHEMBL127331 | — | — | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL335025 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL127331 | — | IC50 | = | 2400.0 | nM | 5.62 |