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Assay Detail

CHEMBL677171

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration of compound against HIV-1 LAI strain in GHOST CXCR4 cell line
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type GHOST CXCR4
Confidence 1 — Organism
Curated By Intermediate

Target

GHOST CXCR4 (CHEMBL612253)
Type CELL-LINE
Organism Homo sapiens

Publication

New bicyclam-GalCer analogue conjugates: synthesis and in vitro anti-HIV activity.
Daoudi JM, Greiner J, Aubertin AM, Vierling P.
Bioorg Med Chem Lett (2004) 14 : 495 -498
PubMed 14698189 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.68 7.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3215411 1 7.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3215411 IC50 = 21.0 nM 7.68