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Assay Detail

CHEMBL677191

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of vWF binding to GPIIb/IIIIa receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 6 — Multiple protein complex / RNA
Curated By Autocuration

Target

Integrin alpha-IIb/beta-3 (CHEMBL2093869)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Tetrahydrothienopyridine derivatives as novel GPIIb/IIIa antagonists
Katano K, Shitara E, Shimizu M, Sasaki K, Miura T, Isomura Y, Kawaguchi M, Ohuchi S, Tsuruoka T
Bioorg Med Chem Lett (1996) 6 : 2601 -2606
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.40 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL313763 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL313763 IC50 = 4000.0 nM 5.40