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Assay Detail

CHEMBL677256

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Relative binding affinity of compound for FK506 binding protein (FKBP)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein.
Becker JW, Rotonda J, Cryan JG, Martin M, Parsons WH, Sinclair PJ, Wiederrecht G, Wong F.
J Med Chem (1999) 42 : 2798 -2804
PubMed 10425089 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.41 9.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL269732 TACROLIMUS ANHYDROUS 4.0 1 9.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL269732 TACROLIMUS ANHYDROUS IC50 = 0.39 nM 9.41