Assay Detail
Binding
CHEMBL677436
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Compound was evaluated In vitro for inhibition of human neutrophil elastase
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of a peptidyl 2,2-difluoro-3-aminopropionate
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.78 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL336171 | — | — | 1 | 9.00 |
| CHEMBL339870 | — | — | 1 | 8.00 |
| CHEMBL130271 | — | — | 1 | 7.85 |
| CHEMBL2371207 | — | — | 1 | 7.36 |
| CHEMBL2371206 | — | — | 1 | 6.70 |
| CHEMBL20397 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL336171 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL339870 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL130271 | — | Ki | = | 14.0 | nM | 7.85 |
| CHEMBL2371207 | — | Ki | = | 44.0 | nM | 7.36 |
| CHEMBL2371206 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL20397 | — | Ki | > | 300000.0 | nM | - |