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Assay Detail

CHEMBL677837

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Functional
Inhibitory activity against mammalian FM3A cell
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type FM3A
Confidence 1 — Organism
Curated By Intermediate

Target

FM3A (CHEMBL614297)
Type CELL-LINE
Organism Mus musculus

Publication

Synthesis of 2-fluoronoraristeromycin and its inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.
Kitade Y, Kojima H, Zulfiqur F, Kim HS, Wataya Y.
Bioorg Med Chem Lett (2003) 13 : 3963 -3965
PubMed 14592485 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.14 7.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL129014 NORARISTEROMYCIN 1 7.14
CHEMBL129469 1 5.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL129014 NORARISTEROMYCIN EC50 = 72.0 nM 7.14
CHEMBL129469 EC50 = 7200.0 nM 5.14