Assay Detail
Functional
CHEMBL677839
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Cytotoxicity of compound was tested against mouse mammary tumor FM3A cells
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | FM3A |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New semisynthetic quassinoids with in vivo antimalarial activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 10 | 10.15 | 10.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL345787 | — | — | 1 | 10.15 |
| CHEMBL155968 | — | — | 1 | - |
| CHEMBL158605 | — | — | 1 | - |
| CHEMBL155758 | — | — | 1 | - |
| CHEMBL140673 | — | — | 1 | - |
| CHEMBL154851 | — | — | 1 | - |
| CHEMBL140809 | BRUCEINE B | — | 1 | - |
| CHEMBL157367 | — | — | 1 | - |
| CHEMBL347315 | — | — | 1 | - |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL345787 | — | EC50 | = | 0.07 | nM | 10.15 |
| CHEMBL155968 | — | EC50 | = | 0.00011 | nM | - |
| CHEMBL158605 | — | EC50 | > | 0.00032 | nM | - |
| CHEMBL155758 | — | EC50 | = | 0.0066 | nM | - |
| CHEMBL140673 | — | EC50 | = | 0.00016 | nM | - |
| CHEMBL154851 | — | EC50 | = | 0.0087 | nM | - |
| CHEMBL140809 | BRUCEINE B | EC50 | = | 0.008 | nM | - |
| CHEMBL157367 | — | EC50 | > | 0.00063 | nM | - |
| CHEMBL347315 | — | EC50 | = | 0.00036 | nM | - |
| CHEMBL76 | CHLOROQUINE | EC50 | = | 0.00032 | nM | - |