Assay Detail
Binding
CHEMBL677979
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Compound was evaluated for the binding affinity to Endothelin A receptor in the porcine aortic smooth muscle
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Endothelin: a new challenge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.26 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL432683 | — | — | 1 | 5.85 |
| CHEMBL314691 | BQ-123 | 2.0 | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL432683 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL314691 | BQ-123 | IC50 | = | 22000.0 | nM | 4.66 |