Assay Detail
Binding
CHEMBL678016
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of L-736,622 from purified resting Fibrinogen Receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Non-peptide glycoprotein IIb/IIIa inhibitors. 17. Design and synthesis of orally active, long-acting non-peptide fibrinogen receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 7.53 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL298655 | — | — | 1 | 8.96 |
| CHEMBL300525 | — | — | 1 | 8.85 |
| CHEMBL40502 | — | — | 1 | 8.74 |
| CHEMBL540024 | — | — | 1 | 6.23 |
| CHEMBL48371 | — | — | 1 | 6.22 |
| CHEMBL300097 | — | — | 1 | 6.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL298655 | — | Kd | = | 1.1 | nM | 8.96 |
| CHEMBL300525 | — | Kd | = | 1.4 | nM | 8.85 |
| CHEMBL40502 | — | Kd | = | 1.8 | nM | 8.74 |
| CHEMBL540024 | — | Kd | = | 590.0 | nM | 6.23 |
| CHEMBL48371 | — | Kd | = | 600.0 | nM | 6.22 |
| CHEMBL300097 | — | Kd | = | 680.0 | nM | 6.17 |