Assay Detail
Binding
CHEMBL678111
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Binding affinity towards endothelial nitric oxide synthase (eNOS)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Potent and selective conformationally restricted neuronal nitric oxide synthase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 3.85 | 3.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1169419 | — | — | 1 | 3.96 |
| CHEMBL161297 | — | — | 1 | 3.89 |
| CHEMBL44833 | — | — | 1 | 3.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1169419 | — | Ki | = | 110000.0 | nM | 3.96 |
| CHEMBL161297 | — | Ki | = | 128000.0 | nM | 3.89 |
| CHEMBL44833 | — | Ki | = | 200000.0 | nM | 3.70 |