Assay Detail
Binding
CHEMBL678520
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro binding affinity against estrone sulfatase in rat liver microsomes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Liver |
| Subcellular | Microsome |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and sulfatase inhibitory activities of (E)- and (Z)-4-hydroxytamoxifen sulfamates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.45 | 4.45 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL33862 | — | — | 1 | 4.45 |
| CHEMBL32172 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL33862 | — | Ki | = | 35900.0 | nM | 4.45 |
| CHEMBL32172 | — | Ki | > | 500000.0 | nM | - |