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Assay Detail

CHEMBL678835

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Fibrinogen receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

Integrin alpha-IIb/beta-3 (CHEMBL2093869)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Cyclic RGD peptide analogues as antiplatelet antithrombotics.
Barker PL, Bullens S, Bunting S, Burdick DJ, Chan KS, Deisher T, Eigenbrot C, Gadek TR, Gantzos R, Lipari MT.
J Med Chem (1992) 35 : 2040 -2048
PubMed 1597855 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.51 7.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL303561 1 7.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL303561 IC50 = 31.0 nM 7.51