Assay Detail
Binding
CHEMBL679016
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Inhibition of binding to human estrogen receptor
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
5-benzylidene-1,2-dihydrochromeno[3,4-f]quinolines as selective progesterone receptor modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.78 | 6.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL717 | MEDROXYPROGESTERONE ACETATE | 4.0 | 1 | 6.03 |
| CHEMBL130141 | — | — | 1 | 5.94 |
| CHEMBL336169 | — | — | 1 | 5.89 |
| CHEMBL335996 | — | — | 1 | 5.72 |
| CHEMBL337856 | — | — | 1 | 5.61 |
| CHEMBL134277 | — | — | 1 | 5.46 |
| CHEMBL132363 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL717 | MEDROXYPROGESTERONE ACETATE | IC50 | = | 924.0 | nM | 6.03 |
| CHEMBL130141 | — | IC50 | = | 1149.0 | nM | 5.94 |
| CHEMBL336169 | — | IC50 | = | 1273.0 | nM | 5.89 |
| CHEMBL335996 | — | IC50 | = | 1885.0 | nM | 5.72 |
| CHEMBL337856 | — | IC50 | = | 2443.0 | nM | 5.61 |
| CHEMBL134277 | — | IC50 | = | 3488.0 | nM | 5.46 |
| CHEMBL132363 | — | IC50 | = | - | nM | - |