Assay Detail
Binding
CHEMBL679311
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for the inhibitory effect against Gamma-amino-N-butyrate transaminase from pig brain
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
4-aminobutyrate aminotransferase, mitochondrial (CHEMBL2266) ↗| Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
Publication
4-Amino-2-(substituted methyl)-2-butenoic acids: substrates and potent inhibitors of gamma-aminobutyric acid aminotransferase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.88 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL349501 | — | — | 1 | 5.30 |
| CHEMBL353363 | — | — | 1 | 4.72 |
| CHEMBL439835 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL349501 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL353363 | — | Ki | = | 19000.0 | nM | 4.72 |
| CHEMBL439835 | — | Ki | = | 24000.0 | nM | 4.62 |