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Assay Detail

CHEMBL679663

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist activity against Gamma-aminobutyric acid type C (GABA-C) receptor derived from bovine retinal RNA expressed in Xenopus oocytes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Bos taurus
Cell Type Oocyte
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

GABA-C receptor (CHEMBL2109242)
Type PROTEIN COMPLEX GROUP
Organism Homo sapiens

Publication

GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology.
Chebib M, Johnston GA.
J Med Chem (2000) 43 : 1427 -1447
PubMed 10780899 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.22 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL33086 t-4-AMINOCROTONIC ACID (TACA) 1 6.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL33086 t-4-AMINOCROTONIC ACID (TACA) Kd = 600.0 nM 6.22