Assay Detail
Binding
CHEMBL679709
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Inhibitory effect against porcine ET-A receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships of cyclic pentapeptide endothelin A receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.46 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL414165 | — | — | 1 | 8.52 |
| CHEMBL133257 | — | — | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL414165 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL133257 | — | IC50 | = | 4.0 | nM | 8.40 |