Assay Detail
Binding
CHEMBL679768
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]BTX binding to guinea pig voltage-dependent sodium channel
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Sodium channel alpha subunits; brain (Types I, II, III) (CHEMBL2096682) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
Anticonvulsant activity of piperidinol and (dialkylamino)alkanol esters.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.04 | 5.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL37310 | — | — | 1 | 5.34 |
| CHEMBL16 | PHENYTOIN | 4.0 | 1 | 4.73 |
| CHEMBL40 | PHENOBARBITAL | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL37310 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL16 | PHENYTOIN | IC50 | = | 18500.0 | nM | 4.73 |
| CHEMBL40 | PHENOBARBITAL | IC50 | > | 10000.0 | nM | - |