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Assay Detail

CHEMBL679970

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was tested for its binding ability to inhibit ErmAM methylase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Design and synthesis of mimics of S-adenosyl-L-homocysteine as potential inhibitors of erythromycin methyltransferases.
Hanessian S, Sgarbi PW.
Bioorg Med Chem Lett (2000) 10 : 433 -437
PubMed 10743942 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.05 5.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL331440 1 5.10
CHEMBL125085 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL331440 Ki = 8000.0 nM 5.10
CHEMBL125085 Ki = 10000.0 nM 5.00