Assay Detail
Functional
CHEMBL679998
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro antagonist activity against U-46,619 induced gel-filtered Platelet (GFP) aggregation at 0.3 uM
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery and optimization of a novel series of thrombin receptor (par-1) antagonists: potent, selective peptide mimetics based on indole and indazole templates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.45 | 4.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL268328 | — | — | 1 | 4.59 |
| CHEMBL7627 | — | — | 1 | 4.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL268328 | — | IC50 | = | 25500.0 | nM | 4.59 |
| CHEMBL7627 | — | IC50 | = | 49100.0 | nM | 4.31 |