Assay Detail
Binding
CHEMBL680036
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Inhibitory concentration against FAP-1 pNPP
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 13 (CHEMBL2976) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Potent reversible inhibitors of the protein tyrosine phosphatase CD45.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.19 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50878 | — | — | 1 | 6.22 |
| CHEMBL51579 | — | — | 1 | 5.36 |
| CHEMBL51314 | — | — | 1 | 5.16 |
| CHEMBL50347 | — | — | 1 | 5.00 |
| CHEMBL51776 | — | — | 1 | 4.92 |
| CHEMBL50627 | — | — | 1 | 4.85 |
| CHEMBL300241 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50878 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL51579 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL51314 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL50347 | — | IC50 | = | 9900.0 | nM | 5.00 |
| CHEMBL51776 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL50627 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL300241 | — | IC50 | = | 15000.0 | nM | 4.82 |