Assay Detail
Binding
CHEMBL680437
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards Trypanosoma cruzi farnesyl pyrophosphate synthase (TcFPPS)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trypanosoma cruzi |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.44 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL322551 | — | — | 1 | 6.10 |
| CHEMBL112840 | — | — | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL322551 | — | Ki | = | 790.0 | nM | 6.10 |
| CHEMBL112840 | — | Ki | = | 16990.0 | nM | 4.77 |