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Assay Detail

CHEMBL680580

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Binding
Inhibitory activity against farnesyl Pyrophosphate Synthase was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Leishmania major
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Farnesyl pyrophosphate synthase (CHEMBL1782)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

3-D QSAR investigations of the inhibition of Leishmania major farnesyl pyrophosphate synthase by bisphosphonates.
Sanders JM, Gómez AO, Mao J, Meints GA, Van Brussel EM, Burzynska A, Kafarski P, González-Pacanowska D, Oldfield E.
J Med Chem (2003) 46 : 5171 -5183
PubMed 14613320 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.96 6.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL340034 1 6.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL340034 IC50 = 110.0 nM 6.96