Assay Detail
Functional
CHEMBL680583
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration required against gastrin releasing peptide receptor (GRP-R) in CHO cells by using FLIPR assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design of selective peptidomimetic agonists for the human orphan receptor BRS-3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.31 | 7.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL438926 | — | — | 1 | 7.47 |
| CHEMBL403317 | — | — | 1 | 7.39 |
| CHEMBL262992 | — | — | 1 | 7.08 |
| CHEMBL3144498 | — | — | 1 | 4.91 |
| CHEMBL3144503 | — | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL438926 | — | EC50 | = | 34.0 | nM | 7.47 |
| CHEMBL403317 | — | EC50 | = | 41.0 | nM | 7.39 |
| CHEMBL262992 | — | EC50 | = | 84.0 | nM | 7.08 |
| CHEMBL3144498 | — | EC50 | = | 12200.0 | nM | 4.91 |
| CHEMBL3144503 | — | EC50 | = | 19100.0 | nM | 4.72 |