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Assay Detail

CHEMBL680920

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory concentration required against Glutamate carboxypeptidase II
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Glutamate carboxypeptidase 2 (CHEMBL1892)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and biological evaluation of hydroxamate-Based inhibitors of glutamate carboxypeptidase II.
Stoermer D, Liu Q, Hall MR, Flanary JM, Thomas AG, Rojas C, Slusher BS, Tsukamoto T.
Bioorg Med Chem Lett (2003) 13 : 2097 -2100
PubMed 12798312 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.70 9.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL47009 1 9.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL47009 Ki = 0.2 nM 9.70