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Assay Detail

CHEMBL681089

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for the inhibitory effect against Gamma-amino-N-butyrate transaminase from bacteria
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bacteria
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

4-aminobutyrate aminotransferase, mitochondrial (CHEMBL2044)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

4-Amino-2-(substituted methyl)-2-butenoic acids: substrates and potent inhibitors of gamma-aminobutyric acid aminotransferase.
Silverman RB, Durkee SC, Invergo BJ.
J Med Chem (1986) 29 : 764 -770
PubMed 3701787 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.05 5.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL353363 1 5.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL353363 Ki = 9000.0 nM 5.05